Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 14/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076408 | 1.00 | MTOR (0.35) | MTORIDH1RXFP1MAPTHTT | |
| SCHEMBL4075542 | 0.87 | MTOR (0.38) | MTORIDH1RXFP1MAPTHTT | |
| SCHEMBL4075732 | 0.87 | MTOR (0.38) | MTORIDH1RXFP1MAPTHTT | |
| SCHEMBL4496745 | 0.86 | IDH1 (0.36) | MTORIDH1MAPTP2RX3P2RX2 | |
| SCHEMBL4076669 | 0.78 | CA1 (0.47) | IDH1MAPT | |
| SCHEMBL4075686 | 0.78 | CA1 (0.47) | IDH1MAPT | |
| SCHEMBL4075212 | 0.78 | CA1 (0.47) | IDH1MAPT | |
| SCHEMBL27774004 | 0.76 | MAPT (0.32) | RXFP1MAPTHTTNPSR1 | |
| SCHEMBL27826411 | 0.76 | MAPT (0.32) | RXFP1MAPTHTTNPSR1 | |
| SCHEMBL4499677 | 0.74 | IDH1 (0.35) | MTORIDH1MAPTP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | claimed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | claimed |
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |