Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966037 | 1.00 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL963095 | 1.00 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL963175 | 0.88 | CNR2 (0.46) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL961865 | 0.88 | CNR2 (0.46) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL964164 | 0.88 | CNR2 (0.46) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL965811 | 0.88 | CNR2 (0.46) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL967097 | 0.87 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL967095 | 0.87 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL16626220 | 0.86 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL16626218 | 0.86 | CNR2 (0.45) | CNR2CNR1HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024349-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Abbott Laboratories (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007140439-A2 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |