Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.30 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082343 | 1.00 | TDP1 (0.36) | TDP1NT5ESMYD2DUT | |
| SCHEMBL4079323 | 0.92 | TDP1 (0.33) | TDP1NT5E | |
| SCHEMBL13722085 | 0.87 | TDP1 (0.38) | TDP1NT5ESMYD2DUT | |
| SCHEMBL20394004 | 0.85 | TDP1 (0.40) | TDP1NT5ESMYD2DUT | |
| SCHEMBL20394005 | 0.85 | TDP1 (0.40) | TDP1NT5ESMYD2DUT | |
| SCHEMBL4078224 | 0.84 | P2RY6 (0.34) | NT5ESMYD2DUT | |
| SCHEMBL4078222 | 0.84 | P2RY6 (0.34) | NT5ESMYD2DUT | |
| SCHEMBL4078216 | 0.81 | — | — | |
| SCHEMBL13721968 | 0.81 | TDP1 (0.35) | TDP1NT5ESMYD2DUT | |
| SCHEMBL707765 | 0.81 | TDP1 (0.35) | TDP1NT5ESMYD2DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |