Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.34 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096600 | 1.00 | P2RY6 (0.43) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL5992442 | 1.00 | P2RY6 (0.43) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4773361 | 0.93 | P2RY6 (0.42) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL25630050 | 0.91 | ABL1 (0.41) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL24513025 | 0.88 | TMIGD3 (0.37) | ABL1RIN1POLBADORA3TYMP | |
| SCHEMBL19814300 | 0.88 | TMIGD3 (0.37) | ABL1RIN1POLBADORA3TYMP | |
| SCHEMBL20394006 | 0.88 | P2RY6 (0.42) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL5859716 | 0.88 | TMIGD3 (0.37) | ABL1RIN1POLBADORA3TYMP | |
| SCHEMBL6878873 | 0.87 | POLB (0.47) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL4083482 | 0.85 | P2RY6 (0.39) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569686-B1 | Compounds and methods for synthesis of bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2009-08-04 | — | — | US | disclosed |