⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383 | 0.96 | — | — | |
| SCHEMBL1446050 | 0.92 | — | — | |
| SCHEMBL20526424 | 0.92 | — | — | |
| SCHEMBL9158859 | 0.92 | — | — | |
| SCHEMBL21333947 | 0.92 | — | — | |
| SCHEMBL21751001 | 0.82 | — | — | |
| SCHEMBL15758518 | 0.79 | — | — | |
| SCHEMBL395705 | 0.77 | — | — | |
| SCHEMBL6660580 | 0.77 | — | — | |
| SCHEMBL2474900 | 0.74 | GRIN2D (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563904-B2 | Synthesis intermediates useful for preparing zolmitriptan | INKE, S.A. (ES) | 2009-07-21 | — | — | US | disclosed |
| US-20080306279-A1 | Synthesis Intermediates Useful For Preparing Zolmitriptan | INKE, S.A. (ES) | 2008-12-11 | — | — | US | disclosed |
| US-7342035-B2 | Reduction, acidification of aniline diazonium salt ; In situ reaction of hydrazine hydrochloride with alpha-keto-delta-valerolactone; Fischer indole synthesis of hydrazone; Transesterification of pyranoindolone; Conversion of hydroxyl group into amino; Saponification, decarboxylation of indolecarboxylate | INKE, S.A. (ES) | 2008-03-11 | — | — | US | disclosed |
| US-7279581-B2 | Process for preparing a pharmaceutically active compound | INKE, S.A. (ES) | 2007-10-09 | — | — | US | disclosed |
| EP-1534705-B1 | PROCESS FOR PREPARING ZOLMITRIPTAN COMPOUNDS | INKE SA (ES) | 2006-07-26 | — | — | EP | disclosed |
| EP-1527053-B8 | PROCESS FOR PREPARING RIZATRIPTAN | INKE SA (ES) | 2006-03-08 | — | — | EP | disclosed |
| US-20060025600-A1 | Process for preparing zolmitriptan compounds | INKE, S.A. (ES) | 2006-02-02 | — | — | US | disclosed |
| EP-1527053-B1 | PROCESS FOR PREPARING RIZATRIPTAN | VITA CIENTIFICA S L (ES) | 2005-12-07 | — | — | EP | disclosed |
| US-20050148778-A1 | Process for preparing a rizatriptan | INKE, S.A. (ES) | 2005-07-07 | — | — | US | disclosed |
| EP-1534705-A1 | PROCESS FOR PREPARING ZOLMITRIPTAN COMPOUNDS | VITA CIENTIFICA, S.L. (ES) | 2005-06-01 | — | — | EP | disclosed |
| EP-1527053-A1 | PROCESS FOR PREPARING RIZATRIPTAN | VITA CIENTIFICA, S.L. (ES) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004014901-A1 | PROCESS FOR PREPARING ZOLMITRIPTAN COMPOUNDS | VITA CIENTIFICA, S.L. (ES) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014877-A1 | PROCESS FOR PREPARING RIZATRIPTAN | VITA CIENTIFICA, S.L. (ES) | 2004-02-19 | — | — | WO | disclosed |