Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 13/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12938681 | 0.94 | TSHR (0.61) | TSHRACHEEPHX2DGKA | |
| SCHEMBL13572560 | 0.91 | TSHR (0.57) | TSHRACHEEPHX2DGKA | |
| SCHEMBL12938679 | 0.90 | TSHR (0.50) | TSHRACHEEPHX2DGKA | |
| SCHEMBL18094634 | 0.89 | TSHR (0.65) | TSHRACHEEPHX2 | |
| SCHEMBL18094781 | 0.89 | TSHR (0.65) | TSHRACHEEPHX2 | |
| SCHEMBL13032957 | 0.89 | TSHR (0.65) | TSHRACHEEPHX2 | |
| SCHEMBL18094783 | 0.89 | TSHR (0.65) | TSHRACHEEPHX2 | |
| SCHEMBL18094652 | 0.89 | TSHR (0.65) | TSHRACHEEPHX2 | |
| SCHEMBL12938677 | 0.88 | TSHR (0.47) | TSHRACHEDGKA | |
| SCHEMBL12938688 | 0.88 | TSHR (0.47) | TSHRACHEDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227195-B1 | METHODS AND KITS FOR MAKING FLEXIBLE DENTAL GUARDS | DENTSPLY INT INC (US) | 2014-08-27 | — | — | EP | disclosed |
| US-20090130624-A1 | Methods and kits for making flexible dental guards | SUN BENJAMIN JIEMIN | 2009-05-21 | — | — | US | disclosed |