SCHEMBL4085826

SCHEMBL4085826

CCC[SiH2]NC(=O)CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10685009 0.73
SCHEMBL3833244 0.71
SCHEMBL1155743 0.67
Hydrochloric Acid SCHEMBL181355 0.65
SCHEMBL6754466 0.64
SCHEMBL2124942 0.64
SCHEMBL10050997 0.64
SCHEMBL16743519 0.62
SCHEMBL1655813 0.62
SCHEMBL7769432 0.61 HDAC3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2009519316-A 2009-05-14 JP claimed
EP-1960003-A2 TARGETED NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING General Electric Company (US) 2008-08-27 EP claimed
US-20070140974-A1 Targeted nanoparticles for magnetic resonance imaging GENERAL ELECTRIC COMPANY (US) 2007-06-21 US claimed
WO-2007069040-A2 TARGETED NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING GENERAL ELECTRIC COMPANY (US) 2007-06-21 WO claimed