⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415648 | 0.81 | — | — | |
| SCHEMBL10912037 | 0.80 | — | — | |
| SCHEMBL3415650 | 0.79 | — | — | |
| SCHEMBL6640081 | 0.79 | — | — | |
| SCHEMBL1078663 | 0.77 | — | — | |
| SCHEMBL26102783 | 0.77 | HCAR2 (0.38) | — | |
| SCHEMBL6646058 | 0.77 | — | — | |
| SCHEMBL2746486 | 0.77 | — | — | |
| SCHEMBL400162 | 0.77 | — | — | |
| SCHEMBL9603874 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359419-A1 | PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS | Pharmacytics B.V. (NL) | 2024-05-01 | — | — | EP | claimed |
| CN-117858882-A | Prodrugs having 1- (disulfanyl) alkoxy-carbonyl units | 药物有限公司 | 2024-04-09 | — | — | CN | claimed |
| EP-3214066-B1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL FLUOROFORMATES | SOLVAY FLUOR GMBH (DE) | 2024-02-21 | — | — | EP | claimed |
| WO-2022271018-A1 | PRODRUGS WITH 1-(DISULFANYL)ALKYLOXY-CARBONYL UNITS | PHARMACYTICS B.V. (NL) | 2022-12-29 | — | — | WO | claimed |
| CN-108250143-A | A kind of benzyl isoquinoline compounds, preparation method and purposes | 四川道珍科技有限公司 | 2018-07-06 | — | — | CN | claimed |
| EP-3214066-A2 | PROCESS FOR THE PREPARATION OF FLUOROALKYL FLUOROFORMATES | Solvay Fluor GmbH (DE) | 2017-09-06 | — | — | EP | claimed |
| WO-2013026777-A1 | FLUOROALKYL S-(FLUORO)ALKYL THIOCARBONATES, A METHOD FOR THE PREPARATION OF FLUOROALKYL S-(FLUORO)ALKYL THIOCARBONATES, AND THEIR USE | SOLVAY SA (BE) | 2013-02-28 | — | — | WO | claimed |
| EP-2454226-A1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL (FLUORO)ALKYL CARBONATES AND CARBAMATES | Solvay Fluor GmbH (DE) | 2012-05-23 | — | — | EP | claimed |
| US-20120116111-A1 | Process for the preparation of fluoroalkyl (fluoro)alkyl carbonates and carbamates | SOLVAY FLUOR GMBH (DE) | 2012-05-10 | — | — | US | claimed |
| WO-2011006822-A1 | PROCESS FOR THE PREPARATION OF FLUOROALKYL (FLUORO)ALKYL CARBONATES AND CARBAMATES | SOLVAY FLUOR GMBH (DE) | 2011-01-20 | — | — | WO | claimed |
| EP-1852414-B1 | Process for the preparation of 4-Hydroxyalkylamino-2-nitro-anisoles | WELLA AG (DE) | 2008-11-26 | — | — | EP | claimed |
| US-7405325-B2 | Process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-29 | — | — | US | claimed |
| WO-2007137785-A2 | PROCESS USEFUL IN THE PREPARATION OF MORPHINAN ANTAGONISTS | ALPHARMA (BERMUDA) INVESTMENTS LTD (BM) | 2007-12-06 | — | — | WO | claimed |
| EP-1852414-A1 | Process for the preparation of 4-Hydroxyalkylamino-2-nitro-anisoles | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | claimed |
| WO-2007122579-A2 | PROCESS FOR THE PREPARATION OF 4-HYDROXYALKYLAMINO-2-NITRO-ANISOLES | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-01 | — | — | WO | claimed |
| US-20070249868-A1 | New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | claimed |
| EP-1730132-A2 | PROCESS FOR PREPARING PHARMACEUTICALLY ACCEPTABLE SALTS OF DULOXETINE AND INTERMEDIATES THEREOF | Teva Pharmaceutical Industries Ltd (IL) | 2006-12-13 | — | — | EP | claimed |
| US-20060194869-A1 | Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2006-08-31 | — | — | US | claimed |
| WO-2006071868-A2 | PROCESS FOR PREPARING PHARMACEUTICALLY ACCEPTABLE SALTS OF DULOXETINE AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-07-06 | — | — | WO | claimed |
| US-5091581-A | Reacting diaminonitrobenzene with chloroalkyl chloroformate | HANS SCHWARZKOPF GMBH (DE) | 1992-02-25 | — | — | US | claimed |