SCHEMBL40860

SCHEMBL40860

CC(C)c1nnc2ccc(-c3ocnc3-c3ccc(F)cc3)cn12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5774497 0.89 MAPK14 (1.00) MAPK14
SCHEMBL5775718 0.88 MAPK14 (1.00) MAPK14
SCHEMBL5775341 0.88 MAPK14 (1.00) MAPK14
SCHEMBL4767945 0.87 MAPK14 (1.00) MAPK14
SCHEMBL4762399 0.87 MAPK14 (1.00) MAPK14
SCHEMBL4764009 0.87 MAPK14 (1.00) MAPK14
SCHEMBL4762527 0.87 MAPK14 (1.00) MAPK14
SCHEMBL4769307 0.86 MAPK14 (1.00) MAPK14
Hydrochloric Acid SCHEMBL4762463 0.86 MAPK14 (0.98) MAPK14
SCHEMBL5771520 0.85 MAPK14 (1.00) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5569 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036726-A Preparation method of triazolopyridine compound 天津辰欣药物研究有限公司 2026-05-15 CN claimed
EP-3597184-B1 INDANONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS OR OPTICAL ISOMERS THEREOF, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING VIRAL DISEASES KOREA RES INST CHEMICAL TECH (KR) 2026-03-04 EP claimed
EP-4688778-A1 1H-PYRROLO[2,3-B]PYRIDIN-4-YL]-2-OXOPYRROLIDINE-3-CARBONITRILE DERIVATIVES AS TYROSINE KINASE 2 (TYK2) INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES Biogen MA Inc. (US) 2026-02-11 EP claimed
US-12527741-B2 Modular dendron micelles for treatment of pulmonary diseases related to fibrosis and viral infection including COVID-19 WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-01-20 US claimed
EP-4654964-A1 SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF The Rockefeller University (US) 2025-12-03 EP claimed
US-20250361432-A1 Slurry Composition for Chemical Mechanical Polishing KCTECH CO LTD (KR) 2025-11-27 US claimed
EP-4653437-A2 NOVEL HETEROCYCLIC COMPOUNDS Innovo Therapeutics Inc. (KR) 2025-11-26 EP claimed
US-20250304558-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-10-02 US claimed
US-12391674-B2 Heterocyclic compounds for the treatment of epilepsy OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-08-19 US claimed
CN-120025316-A Compound for targeted degradation of ALK protein, and preparation method and application thereof 成都分迪药业有限公司 2025-05-23 CN claimed
CN-1035116-A Heterocyclic type oxo-2 guanidine-acetic acid PFIZER (US) 1989-08-30 CN claimed
EP-0322153-A2 Heterocyclic oxophtalazinyl acetic acids PFIZER INC. (US) 1989-06-28 EP claimed
EP-0150419-B1 2H-v-triazolyl[4,5-b]pyridines and their use BASF Aktiengesellschaft (DE) 1988-07-27 EP claimed
EP-0244201-A2 3-Hydroxypyridines SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1987-11-04 EP claimed
EP-0227932-A1 Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1987-07-08 EP claimed
EP-0228061-A2 Cephem compounds Takeda Chemical Industries, Ltd. (JP) 1987-07-08 EP claimed
EP-0025603-B1 TRIAZOLO (4,3-A)PYRIDIN-3(2H)-ONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Bristol-Myers Company (US) 1983-11-02 EP claimed
US-4302454-A Cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-11-24 US claimed
US-4266060-A ANTITUMOR ANTIVIRAL AGENTS FOR TREATMENT OF CANCER AGENCE NATIONALE DE VAL ORISATION DE LA RECHERCHE (ANVAR) (FR) 1981-05-05 US claimed
EP-0025603-A1 Triazolo (4,3-a)pyridin-3(2H)-ones, process for their preparation and pharmaceutical compositions containing them Bristol-Myers Company (US) 1981-03-25 EP claimed