Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1218993 | 0.87 | EGLN1 (0.61) | EGLN1 | |
| SCHEMBL2882107 | 0.80 | SMN1; SMN2 (0.42) | EGLN1 | |
| SCHEMBL2887667 | 0.79 | EGLN1 (0.50) | EGLN1EGLN2 | |
| SCHEMBL1218607 | 0.74 | EGLN1 (0.79) | EGLN1 | |
| SCHEMBL2880629 | 0.74 | EGLN1 (0.59) | EGLN1EGLN2 | |
| SCHEMBL1218586 | 0.72 | EGLN1 (0.66) | EGLN1 | |
| SCHEMBL2886900 | 0.72 | EGLN1 (0.61) | EGLN1EGLN2 | |
| SCHEMBL1219405 | 0.71 | EGLN1 (0.70) | EGLN1EGLN2 | |
| SCHEMBL2886255 | 0.71 | EGLN1 (0.65) | EGLN1EGLN2 | |
| SCHEMBL1214993 | 0.70 | EGLN1 (0.54) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016078-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007115315-A2 | PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS AS HIF MODULATORS | FIBROGEN, INC. (US) | 2007-10-11 | — | — | WO | disclosed |