SCHEMBL4088048

SCHEMBL4088048

Clc1ccc(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.70
LMNA P02545 2/20 0.57
CYP2A6 P11509 1/20 0.57
TSHR P16473 2/20 0.55
MAPK1 P28482 2/20 0.55
HIF1A Q16665 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 1/20 0.52
HPGD P15428 1/20 0.52
ADRB2 P07550 1/20 0.52
IDO1 P14902 4/20 0.48
TDO2 P48775 3/20 0.48
BRD4 O60885 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7782034 0.97 CYP19A1 (0.67) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL3695767 0.88 CYP19A1 (0.59) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL673181 0.88 CYP19A1 (0.59) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL36217 0.86 CYP19A1 (0.56) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL5010075 0.86 CYP19A1 (0.56) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL31409234 0.86 CYP19A1 (0.56) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL11538836 0.84 CYP19A1 (1.00) CYP19A1LMNATSHRMAPK1HIF1A
SCHEMBL22388390 0.82 CYP1A2 (0.64) CYP19A1LMNATSHRMAPK1HIF1A
SCHEMBL13191313 0.82 CYP19A1 (0.52) CYP19A1LMNACYP2A6TSHRMAPK1
SCHEMBL3696526 0.80 CYP19A1 (0.50) CYP19A1LMNACYP2A6TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119177055-A Ultra-long durable UV (ultraviolet) coating for proportional valve core armature and preparation method thereof 上海安弗柯林工业科技有限公司 2024-12-24 CN claimed
CN-112724373-B Functional organic porous polymer and preparation method and application thereof 山东大学 2021-09-21 CN claimed
CN-112724373-A Functional organic porous polymer and preparation method and application thereof 山东大学 2021-04-30 CN claimed
EP-0717080-B1 Method for the preparation of triphenylmethan colorants CLARIANT GMBH (DE) 2001-10-17 EP claimed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP claimed
CN-119177055-A Ultra-long durable UV (ultraviolet) coating for proportional valve core armature and preparation method thereof 上海安弗柯林工业科技有限公司 2024-12-24 CN disclosed
CN-112724373-B Functional organic porous polymer and preparation method and application thereof 山东大学 2021-09-21 CN disclosed
CN-112724373-A Functional organic porous polymer and preparation method and application thereof 山东大学 2021-04-30 CN disclosed
EP-2693444-B1 AN ELECTRICALLY CONDUCTIVE COMPOSITION, AN ELECTRICALLY CONDUCTIVE FILM USING THE COMPOSITION AND A METHOD OF PRODUCING THE SAME FUJIFILM CORP (JP) 2019-03-13 EP disclosed
EP-2692762-B1 ELECTRICALLY CONDUCTIVE COMPOSITION, ELECTRICALLY CONDUCTIVE FILM USING SAID COMPOSITION AND PRODUCTION METHOD THEREFOR FUJIFILM CORP (JP) 2017-09-27 EP disclosed
US-9445501-B2 Electrically conductive composition, electrically conductive film using the composition and a method of producing the same FUJIFILM CORPORATION (JP) 2016-09-13 US disclosed
US-9445501-B2 Electrically conductive composition, electrically conductive film using the composition and a method of producing the same FUJIFILM CORPORATION (JP) 2016-09-13 US disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
US-4678613-A Process for the purification of triphenylmethane compounds PMC SPECIALTIES GROUP, INC. (US) 1987-07-07 US disclosed
US-4448446-A FORMING THE SALT AND REACTING WITH A3 BASE, DISSOLVING THE CARBINOL FORM IN AN ORGANIC SOLVENT THE SHERWIN-WILLIAMS COMPANY (US) 1984-05-15 US disclosed
US-4444592-A Pigment compositions and processes therefor THE SHERWIN-WILLIAMS COMPANY (US) 1984-04-24 US disclosed