Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.55 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.55 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.55 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.55 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.55 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | NPC1 | O15118 | 1/20 | 0.81 |
| ▸ | RAB9A | P51151 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4086081 | 1.00 | HTT (0.81) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Bromide SCHEMBL4089488 | 1.00 | HTT (0.81) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| Bromide SCHEMBL18094953 | 0.98 | KMT2A (0.81) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL13928786 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL21777162 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL3217713 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL3198349 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL3215274 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL19618006 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL3218482 | 0.96 | KMT2A (0.84) | HTTSMN1; SMN2LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7500895-B2 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2009-03-10 | — | — | US | disclosed |
| CN-1790772-A | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORP (JP) | 2006-06-21 | — | — | CN | disclosed |
| US-20060127563-A1 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2006-06-15 | — | — | US | disclosed |
| US-20050287392-A1 | Organic electroluminescent device, method for producing the same, and electronic apparatus | SEIKO EPSON CORPORATION (JP) | 2005-12-29 | — | — | US | disclosed |