Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413592 | 0.94 | CYP2C19 (0.55) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23603829 | 0.92 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1008355 | 0.92 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16371587 | 0.92 | CYP2C19 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1149087 | 0.86 | CYP2C19 (0.61) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7909121 | 0.86 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6306047 | 0.86 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28965534 | 0.84 | CYP2C19 (0.57) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31163814 | 0.83 | PTGER1 (0.46) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3078147 | 0.81 | CYP2C19 (0.64) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670460-B1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-26 | — | — | EP | disclosed |
| US-7517900-B2 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-04-14 | — | — | US | disclosed |
| US-4659370-A | Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4614536-A | Certain pyridyloxy-phenoxy-propionate derivatives, herbicidal compositions containing same and their herbicidal method of use | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1986-09-30 | — | — | US | disclosed |
| EP-0092112-B1 | SUBSTITUTED PHENOXY PROPIONATES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-03-06 | — | — | EP | disclosed |
| US-4500346-A | Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-02-19 | — | — | US | disclosed |
| EP-0092112-A1 | Substituted phenoxy propionates | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4033965-A | DISPERSE | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080087-A1 | Pyrazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | CYP2C19 216/4885CYP1A2 299/4885CYP3A4 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.