Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.57 |
| ▸ | PYGL | P06737 | 9/20 | 0.46 |
| ▸ | PYGM | P11217 | 6/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940961 | 1.00 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL2940963 | 1.00 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL2937416 | 0.92 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL2937418 | 0.92 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL4095043 | 0.92 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL10476669 | 0.84 | SMYD3 (0.59) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL12035448 | 0.84 | SMYD3 (0.59) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL2942607 | 0.84 | SMYD3 (0.59) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL2942606 | 0.84 | SMYD3 (0.59) | SMYD3PYGLPYGMEHMT2CYP51A1 | |
| SCHEMBL4095708 | 0.82 | SMYD3 (0.57) | SMYD3PYGLPYGMEHMT2CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270557-B1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20090227789-A1 | ETHYLENEDIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-10 | — | — | US | disclosed |
| US-7192968-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20060004009-A1 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| US-20040122063-A1 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004009-A1 | Ethylenediamine derivatives | F2, ECE1, MLLT1 | SMYD3 995/4885PYGL 3056/4885PYGM 4146/4885 |
| US-20090227789-A1 | ETHYLENEDIAMINE DERIVATIVES | F2, ECE1, MLLT1 | SMYD3 995/4885PYGL 3056/4885PYGM 4146/4885 |
| US-20040122063-A1 | Ethylenediamine derivatives | ECE1, F2, ECE2 | SMYD3 1262/4885PYGL 2722/4885PYGM 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.