Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096704 | 0.89 | PTGER1 (0.89) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4085520 | 0.88 | PTGER1 (0.74) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13694752 | 0.87 | PTGER1 (0.60) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4091451 | 0.87 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13693293 | 0.86 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4092108 | 0.85 | PTGER1 (0.70) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL13693298 | 0.85 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4092606 | 0.85 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4095687 | 0.85 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4095567 | 0.85 | PTGER1 (1.00) | PTGER1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239845-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | CONWAY ELIZABETH ANN | 2009-09-24 | — | — | US | disclosed |
| US-20090239845-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | CONWAY ELIZABETH ANN | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239845-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | PTGER1, PTGDR, PTGIR | PTGER1 1/4885CYP2C9 189/4885CYP1A2 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.