SCHEMBL4091333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4095546	0.90	HSP90AB1 (0.38)	HSP90AB1ADORA2AKCNH2ADORA1LRRK2
	SCHEMBL4092353	0.90	SRC (0.38)	HPGDUSP2HSP90AB1SMN1; SMN2ADORA2A
	SCHEMBL15101685	0.90	HPGD (0.40)	HPGDUSP2HSP90AB1SMN1; SMN2LMNA
	SCHEMBL4094726	0.82	LRRK2 (0.41)	HPGDHSP90AB1ADORA2AADORA1LRRK2
	SCHEMBL13928062	0.80	HPGD (0.40)	HPGDUSP2SMN1; SMN2ADORA2APOLB
	SCHEMBL14642115	0.80	HPGD (0.42)	HPGDUSP2SMN1; SMN2LMNAPOLB
	SCHEMBL4086685	0.80	HSP90AB1 (0.41)	HSP90AB1ADORA2APOLBADORA1
	SCHEMBL4086696	0.79	HSP90AB1 (0.43)	HSP90AB1
	SCHEMBL4095634	0.78	PTK2 (0.42)	—
	SCHEMBL4093474	0.77	HSP90AB1 (0.43)	HPGDHSP90AB1ALDH1A1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.