Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080464 | 0.86 | AR (0.49) | ARSRD5A2KCNH2 | |
| SCHEMBL4082848 | 0.86 | AR (0.67) | ARSRD5A2KCNH2 | |
| SCHEMBL4081425 | 0.82 | AR (0.55) | ARSRD5A2KCNH2 | |
| SCHEMBL4086544 | 0.81 | AR (0.56) | ARSRD5A2KCNH2 | |
| SCHEMBL4087751 | 0.81 | AR (0.53) | ARSRD5A2KCNH2 | |
| SCHEMBL4087744 | 0.80 | AR (0.58) | ARSRD5A2KCNH2 | |
| SCHEMBL14271704 | 0.80 | AR (0.60) | ARSRD5A2KCNH2 | |
| SCHEMBL4630379 | 0.80 | AR (0.60) | ARSRD5A2KCNH2 | |
| SCHEMBL4084737 | 0.80 | AR (0.53) | ARSRD5A2KCNH2 | |
| SCHEMBL4077889 | 0.80 | AR (0.57) | ARSRD5A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482357-B2 | 17-acetamido-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2009-01-27 | — | — | US | disclosed |