⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786 | 1.00 | — | — | |
| SCHEMBL28489961 | 0.97 | — | — | |
| Acetic Acid SCHEMBL19331447 | 0.94 | FFAR3 (0.44) | — | |
| SCHEMBL5573998 | 0.76 | — | — | |
| SCHEMBL10789600 | 0.74 | — | — | |
| SCHEMBL14935695 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL8627389 | 0.71 | — | — | |
| SCHEMBL618275 | 0.71 | — | — | |
| SCHEMBL570228 | 0.69 | — | — | |
| SCHEMBL1259537 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024144735-A1 | A MICROENCAPSULATED FOOD SUPPLEMENT WITH PROBIOTIC MICROORGANISMS | CHIVALRIC REGULUS BIYOTEKNOLOJI ANONIM SIRKETI (TR) | 2024-07-04 | — | — | WO | disclosed |
| CN-109072217-A | For treating methylmalonyl-CoA isomerase (MCM) fusion constructs of illness relevant to MCM defect | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20130101569-A1 | HAIR GROWTH STIMULANT | WESTON ANTHONY R (US) | 2013-04-25 | — | — | US | disclosed |
| CN-103059100-A | New peptides useful as dual caspase-2/-6 inhibitor and biological application thereof | THERAPTOSIS S A | 2013-04-24 | — | — | CN | disclosed |
| US-8324173-B2 | Peptides useful as dual caspase-2/-6 inhibitors and their biological applications | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-12-04 | — | — | US | disclosed |
| US-20120021990-A1 | PEPTIDES USEFUL AS DUAL CASPASE-2/-6 INHIBITORS AND THEIR BIOLOGICAL APPLICATIONS | CHAUVIER DAVID (FR) | 2012-01-26 | — | — | US | disclosed |
| US-20090042805-A1 | Peptides Useful As Dual Caspase-2/-6 Inhibitors And Their Biological Applications | CHIESI FARMACEUTICI S.P.A. (IT) | 2009-02-12 | — | — | US | disclosed |
| CN-100371336-C | Pyrrole derivatives for the treatment of cytokine mediated diseases | SANKYO CO (JP) | 2008-02-27 | — | — | CN | disclosed |
| EP-1817328-A2 | NEW PEPTIDES USEFUL AS DUAL CASPASE-2/-6 INHIBITORS AND THEIR BIOLOGICAL APPLICATIONS | Theraptosis S.A. (FR) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056487-A2 | PEPTIDES USEFUL AS DUAL CASPASE-2/-6 INHIBITORS AND THEIR BIOLOGICAL APPLICATIONS | THERAPTOSIS S.A. (FR) | 2006-06-01 | — | — | WO | disclosed |
| US-20060110789-A1 | Methods to mediate polyketide synthase module effectiveness | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-05-25 | — | — | US | disclosed |
| US-7001748-B2 | Methods of making polyketides using hybrid polyketide synthases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2006-02-21 | — | — | US | disclosed |
| CN-1553911-A | pyrrole derivatives, their preparation and their therapeutic use | ������������ʽ���� | 2004-12-08 | — | — | CN | disclosed |
| WO-2003076581-A2 | METHODS TO MEDIATE POLYKETIDE SYNTHASE MODULE EFFECTIVENESS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2003-09-18 | — | — | WO | disclosed |
| US-20030068676-A1 | Methods to mediate polyketide synthase module effectiveness | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-10 | — | — | US | disclosed |