Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112468 | 0.94 | CA12 (0.60) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL4539930 | 0.87 | CA12 (0.68) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL28980953 | 0.87 | CA12 (0.57) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL1067321 | 0.86 | CA12 (0.56) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL29894726 | 0.85 | TDP1 (0.50) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL27883384 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL572949 | 0.84 | TDP1 (0.56) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL11888006 | 0.83 | TDP1 (0.53) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL25095054 | 0.83 | TDP1 (0.58) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL25736733 | 0.83 | CA12 (0.56) | CA12CA1CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214101-A1 | Targeted Nanostructures for Cellular Imaging | WILLIAM MARSH RICE UNIVERSITY | 2009-08-27 | — | — | US | disclosed |
| WO-2007143558-A1 | TARGETED NANOSTRUCTURES FOR CELLULAR IMAGING | WILLIAM MARSH RICE UNIVERSITY (US) | 2007-12-13 | — | — | WO | disclosed |