SCHEMBL409247

SCHEMBL409247

CCOc1ccc(C(COCc2cccc(Oc3ccccc3)c2)C(F)(F)F)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.51
CETP P11597 5/20 0.49
LTA4H P09960 1/20 0.48
FFAR4 Q5NUL3 1/20 0.42
TP53 P04637 1/20 0.40
PKM P14618 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561406 1.00 FFAR1 (0.51) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL9570819 0.93 FFAR1 (0.44) FFAR1CETPLTA4HTP53PKM
SCHEMBL9570818 0.93 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL9570568 0.93 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL409736 0.92 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL9570619 0.92 FFAR1 (0.44) FFAR1CETPLTA4HMRGPRX4
SCHEMBL9862593 0.92 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL118655 0.92 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53
SCHEMBL9570636 0.92 FFAR1 (0.44) FFAR1CETPLTA4HMRGPRX4
SCHEMBL29370536 0.92 FFAR1 (0.44) FFAR1CETPLTA4HFFAR4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225607-A Multistage etherification or dehydrohalogenation and reductive dechlorination IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-07-06 US claimed
EP-0415568-A2 Insecticidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-06 EP claimed
JP-1068303-A None JP disclosed
JP-3148201-A None JP disclosed
JP-1006230-A None JP disclosed
EP-2376219-B1 METHOD FOR CONTROLLING WATER EVAPORATION UNIV MELBOURNE (AU) 2018-03-14 EP disclosed
US-8696987-B2 Method for controlling water evaporation POLYMERS CRC LTD (AU) 2014-04-15 US disclosed
US-20120018387-A1 METHOD FOR CONTROLLING WATER EVAPORATION POLYMERS CRC LTD (AU) 2012-01-26 US disclosed
EP-2376219-A1 METHOD FOR CONTROLLING WATER EVAPORATION Polymers CRC Limited (AU) 2011-10-19 EP disclosed
EP-0646314-B1 Sustained release pesticidal or plant growth regulating composition SUMITOMO CHEMICAL CO (JP) 2004-08-11 EP disclosed
EP-0847691-B1 Granular pesticidal composition SUMITOMO CHEMICAL CO (JP) 2002-09-25 EP disclosed
EP-0415568-A2 Insecticidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-06 EP disclosed
US-4988826-A Fluoroalkylstyrene derivatives as intermediates for insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-29 US disclosed
US-4891450-A FLUORINE-CONTAINING ARYLALKENES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-01-02 US disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
JP-S6468303-A AGRICULTURAL INSECTICIDE COMPOSITION SUMITOMO CHEMICAL CO 1989-03-14 JP disclosed
EP-0280383-A1 Process for intermediates for insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-31 EP disclosed
EP-0276558-A2 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-03 EP disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed
EP-0211561-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-02-25 EP disclosed