Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924592 | 0.85 | P2RY12 (0.79) | P2RY12ALDH1A1 | |
| SCHEMBL4096828 | 0.83 | P2RY12 (0.67) | P2RY12 | |
| SCHEMBL4003396 | 0.79 | P2RY12 (0.79) | P2RY12 | |
| SCHEMBL4094945 | 0.78 | P2RY12 (0.68) | P2RY12 | |
| SCHEMBL3927702 | 0.77 | P2RY12 (0.72) | P2RY12ALDH1A1 | |
| SCHEMBL4097782 | 0.75 | P2RY12 (1.00) | P2RY12ALDH1A1 | |
| SCHEMBL4002120 | 0.74 | P2RY12 (0.51) | P2RY12ALDH1A1 | |
| SCHEMBL4001587 | 0.74 | P2RY12 (0.77) | P2RY12ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL3927436 | 0.72 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL3921936 | 0.71 | P2RY12 (1.00) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186876-A1 | Pyridine Analogues II | ASTRAZENECA AB (SE) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186876-A1 | Pyridine Analogues II | P2RY12, P2RY11, P2RY6 | P2RY12 1/4885ALDH1A1 1602/4885LMNA 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.