Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 9/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.65 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303641 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13303629 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13303673 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL409667 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL6540887 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13303654 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL409666 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12052455 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13303684 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL410119 | 1.00 | SLC6A4 (0.67) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-20120065408-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-03-15 | — | — | US | disclosed |
| US-7754897-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2010-07-13 | — | — | US | disclosed |
| US-20070015924-A1 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065408-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
| US-20070015924-A1 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CYP2D6, CYP3A43, CYP2F1 | SLC6A4 919/4885KCNA5 56/4885SCN5A 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.