⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833717 | 0.85 | — | — | |
| SCHEMBL28208145 | 0.74 | — | — | |
| SCHEMBL27673515 | 0.74 | — | — | |
| SCHEMBL19264995 | 0.69 | — | — | |
| SCHEMBL27514156 | 0.67 | — | — | |
| SCHEMBL27639165 | 0.67 | — | — | |
| SCHEMBL27334261 | 0.66 | — | — | |
| SCHEMBL30728592 | 0.66 | — | — | |
| SCHEMBL8760979 | 0.65 | — | — | |
| SCHEMBL746990 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262240-B | For antineoplastic 3,5-diphenylmethylene-4-derivative of piperidone and preparation method thereof | BINZHOU MEDICAL UNIVERSITY (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-104262240-A | Antitumor 3,5-diphenylmethylene-4-piperidone derivative and preparation method thereof | BINZHOU MEDICAL COLLEGE | 2015-01-07 | — | — | CN | claimed |
| CN-104230796-A | Anti-tumor 3, 5-di(2-bromo-4, 5-dimethoxyl benzylidene)-4-piperidone derivatives and preparation method thereof | BINZHOU MEDICAL COLLEGE | 2014-12-24 | — | — | CN | claimed |
| CN-103288723-A | Sulfonamide hapten, and preparation method and application thereof | BEIJING KWINBON BIOTECH CO LTD | 2013-09-11 | — | — | CN | claimed |
| CN-106565777-A | Preparation method of thiophosphate | 山东科技大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106282125-A | Hybridoma cell strain NaN 1 and the application thereof of anti-sulfa antibiotics monoclonal antibody is secreted in one strain | 江南大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-103055327-B | A kind of for fluorescence imaging with the bifunctional contrast agents of nuclear magnetic resonance | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2016-12-14 | — | — | CN | disclosed |
| CN-106146362-A | Method for synthesizing C-7280948 | 南京理工大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-105560256-A | Pharmaceutical composition comprising aminobenzenesulfone derivatives for treating diseases associated with demyelination of neurons | SAMSUNG ELECTRONICS CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-104262240-B | For antineoplastic 3,5-diphenylmethylene-4-derivative of piperidone and preparation method thereof | BINZHOU MEDICAL UNIVERSITY (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-105272888-A | Bis-arylalkenylalkyl acid compound, and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-27 | — | — | CN | disclosed |
| CN-105175323-A | Method for preparing 2-(4-acetamidobenzenesulfonyl)amidopyridine | ZHEJIANG HISOAR PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | disclosed |
| US-5514691-A | N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin | IMMUNOPHARMACEUTICS, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0699191-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| CN-1112116-A | Novel sulfonamidodioxepanes, methods of preparation, intermediates, salts and use thereof | PLIVA PHARM & CHEM WORKS (HR) | 1995-11-22 | — | — | CN | disclosed |
| CN-1106982-A | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1995-08-16 | — | — | CN | disclosed |
| CN-1027640-C | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | ICI AMERICA INC (US) | 1995-02-15 | — | — | CN | disclosed |
| WO-1994027979-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | IMMUNOPHARMACEUTICS, INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| CN-1087347-A | The new sulfonamide inhibitors of aspartyl protease | VERTEX PHARMA (US) | 1994-06-01 | — | — | CN | disclosed |
| CN-86101066-A | Process for producing novel trifluoromethyl ketone substituted peptide derivatives | — | 1986-11-05 | — | — | CN | disclosed |