Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092153 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL4086456 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL2718021 | 0.89 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL4085486 | 0.83 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL4104637 | 0.83 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL4099393 | 0.81 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL4104277 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL4101744 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL4093343 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL15437009 | 0.80 | PIK3CD (0.63) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061696-A1 | 5 -CYANO-4, 6 -DIAMINOPYRIMIDINE OR 6 -AMINOPURINE DERIVATIVES AS PI3K- DELTA INHIBITORS | AMGEN INC. (US) | 2012-05-10 | — | — | WO | disclosed |