Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990162 | 0.89 | KDM4E (0.72) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL8025519 | 0.86 | KDM4E (0.79) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL4278138 | 0.85 | KDM4E (1.00) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| Acetic Acid SCHEMBL2478031 | 0.83 | KDM4E (0.67) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL990879 | 0.83 | KDM4E (0.64) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL3654274 | 0.81 | KDM4E (0.61) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL12200072 | 0.80 | KDM4E (0.58) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL27961569 | 0.80 | KDM4E (0.72) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27961566 | 0.79 | KDM4E (0.70) | KDM4EGLARCE1CYP1A2CYP3A4 | |
| SCHEMBL2958134 | 0.78 | KDM4E (0.63) | KDM4EGLARCE1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221829-A1 | 3,4-Dihydroisoquinolinium Salt Derivatives | HANWHA CHEMICAL CORPORATION (KR) | 2009-09-03 | — | — | US | disclosed |
| EP-1896419-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006129978-A1 | 3,4-DIHYDROISOQUINOLINIUM SALT DERIVATIVES | HANWHA CHEMICAL CORPORATION (KR) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221829-A1 | 3,4-Dihydroisoquinolinium Salt Derivatives | KCNQ3, KCNQ1, KCNQ2 | KDM4E 1933/4885GLA 3270/4885RCE1 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.