Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cephalexin Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.98 |
| ▸ | MAPT | P10636 | 7/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.98 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.98 |
| ▸ | HPGD | P15428 | 3/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.98 |
| ▸ | BLM | P54132 | 2/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.98 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.98 |
| ▸ | HTR2B | P41595 | 1/20 | 0.98 |
| ▸ | MEN1 | O00255 | 4/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | ESR1 | P03372 | 1/20 | 0.83 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.83 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cephalexin Anhydrous SCHEMBL5489216 | 1.00 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL5049268 | 1.00 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL27562810 | 1.00 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL5049273 | 1.00 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL582342 | 0.99 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL27742537 | 0.99 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL10529259 | 0.99 | HSD17B10 (0.96) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL4928314 | 0.99 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL4928321 | 0.99 | HSD17B10 (0.98) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL2961 | 0.99 | HSD17B10 (1.00) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2359 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| US-20240173512-A1 | METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS | STREETERVILLE CAPITAL, LLC | 2024-05-30 | — | — | US | claimed |
| US-11890421-B2 | Methods for potentiating antimicrobial agents | BEYOND AIR LTD (IL) | 2024-02-06 | — | — | US | claimed |
| CN-117384259-A | Cell penetrating peptides based on influenza virus M2 proteins | 中国医学科学院基础医学研究所 | 2024-01-12 | — | — | CN | claimed |
| CN-114053206-A | Medicinal floating preparation and preparation method thereof | 常州恒邦药业有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-114053207-A | Sustained-release pharmaceutical composition and preparation method thereof | 常州恒邦药业有限公司 | 2022-02-18 | — | — | CN | claimed |
| US-20220008334-A1 | GASTRIC RETENTIVE DEVICES | CLEXIO BIOSCIENCES LTD. (IL) | 2022-01-13 | — | — | US | claimed |
| US-11147766-B2 | Gastric retentive devices | CLEXIO BIOSCIENCES LTD. (IL) | 2021-10-19 | — | — | US | claimed |
| CN-112912386-A | Cell penetrating peptide based on influenza virus M2 protein | 中国医学科学院基础医学研究所 | 2021-06-04 | — | — | CN | claimed |
| US-20200246573-A1 | NITRIC OXIDE INHALATION THERAPY FOR INFANTS WITH BRONCHIOLITIS | STREETERVILLE CAPITAL, LLC | 2020-08-06 | — | — | US | claimed |
| US-20020188196-A1 | Cavity-filling biopsy site markers | SENORX, INC. | 2002-12-12 | — | — | US | claimed |
| US-6245735-B1 | CONJUGATE OF ANTIBIOTIC AND POLYPEPTIDE OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR OR LIPOPOLYSACCHARIDE BINDING FRAGMENT | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2001-06-12 | — | — | US | claimed |
| EP-0976755-A1 | Improvements in or relating to beta lactam production | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2000-02-02 | — | — | EP | claimed |
| EP-0528941-A4 | PROCESS FOR PREPARING CEPHALEXIN MONOHYDRATE | BIOCRAFT LABORATORIES INC (US) | 1994-07-06 | — | — | EP | claimed |
| EP-0528941-A1 | PROCESS FOR PREPARING CEPHALEXIN MONOHYDRATE | BIOCRAFT LABORATORIES, Inc. (US) | 1993-03-03 | — | — | EP | claimed |
| US-5142043-A | PROCESS FOR PREPARING CEPHALEXIN MONOHYDRATE | BIOCRAFT LABORATORIES, INC. (US) | 1992-08-25 | — | — | US | claimed |
| WO-1991017166-A1 | PROCESS FOR PREPARING CEPHALEXIN MONOHYDRATE | BIOCRAFT LABORATORIES, INC. (US) | 1991-11-14 | — | — | WO | claimed |
| EP-0143658-B1 | IMPROVEMENTS IN OR RELATING TO CEPHALOSPORIN DERIVATIVES | ELI LILLY AND COMPANY (US) | 1989-03-22 | — | — | EP | claimed |
| US-4775751-A | Process for cephalexin hydrochloride alcoholates | ELI LILLY & COMPANY (US) | 1988-10-04 | — | — | US | claimed |
| US-4615698-A | Total agent osmotic delivery system | ALZA CORPORATION (US) | 1986-10-07 | — | — | US | claimed |