⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31220901 | 0.89 | — | — | |
| SCHEMBL1735081 | 0.76 | — | — | |
| SCHEMBL215024 | 0.76 | — | — | |
| SCHEMBL2165425 | 0.74 | — | — | |
| Water SCHEMBL5014877 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL442651 | 0.73 | — | — | |
| SCHEMBL2799985 | 0.73 | — | — | |
| Fluoride SCHEMBL28669198 | 0.73 | — | — | |
| SCHEMBL4674240 | 0.70 | — | — | |
| SCHEMBL7961789 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080307794-A1 | GUANIDINE BASED FUEL SYSTEM AND METHOD OF OPERATING A COMBUSTION SYSTEM | PUREGENERATION (UK) LTD (GB) | 2008-12-18 | — | — | US | claimed |
| US-20080286165-A1 | Guanidine Based Composition and System for Same | GRAUPNER ROBERT K | 2008-11-20 | — | — | US | claimed |
| EP-1742871-A2 | GUANIDINE BASED COMPOSITION AND SYSTEM FOR SAME | Graupner, Robert K. (US) | 2007-01-17 | — | — | EP | claimed |
| WO-2005108289-A2 | GUANIDINE BASED COMPOSITION AND SYSTEM FOR SAME | GRAUPNER ROBERT K (US) | 2005-11-17 | — | — | WO | claimed |
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | claimed |
| US-4978684-A | ADMINISTERING AMINOGUANIDINE DERIVATIVE | THE ROCKEFELLER UNIVERSITY (US) | 1990-12-18 | — | — | US | claimed |
| EP-0327919-A2 | Method and agents for preventing staining of teeth | THE ROCKEFELLER UNIVERSITY (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | claimed |
| CN-104080452-A | Methods of treating HCV infection with small molecule CHK2 inhibitors | US OF AMERICA AS REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVIC | 2014-10-01 | — | — | CN | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| US-6599943-B1 | Preventive treatment, related to the radical generating nature of the xanthine dehydrogenase/xanthine oxidase | WAPHARM AB (SE) | 2003-07-29 | — | — | US | disclosed |
| EP-1007025-A1 | USE OF HYDROXYGUANIDINES | Wa Pharm AB (SE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998023267-A1 | USE OF HYDROXYGUANIDINES | WAPHARM AB (SE) | 1998-06-04 | — | — | WO | disclosed |
| WO-1997045108-A1 | GUANIDINO DERIVATIVES AS INHIBITORS OF THE CYTOTOXIC EFFECT OF PEROXYNITRITE | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 1997-12-04 | — | — | WO | disclosed |