⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28105943 | 0.97 | — | — | |
| SCHEMBL25629324 | 0.89 | HDAC8 (0.61) | — | |
| Formic Acid SCHEMBL31492518 | 0.89 | HDAC8 (0.61) | — | |
| SCHEMBL4787787 | 0.88 | — | — | |
| SCHEMBL17980862 | 0.88 | — | — | |
| SCHEMBL13841217 | 0.87 | HDAC8 (0.58) | — | |
| SCHEMBL15200298 | 0.87 | HDAC8 (0.58) | — | |
| SCHEMBL5140992 | 0.85 | HDAC6 (1.00) | — | |
| SCHEMBL3077769 | 0.85 | HDAC6 (1.00) | — | |
| SCHEMBL18513474 | 0.85 | HDAC6 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667709-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI Foundation, Inc. (US) | 2013-12-04 | — | — | EP | claimed |
| WO-2012103008-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2012-08-02 | — | — | WO | claimed |
| US-4207091-A | HYDROZAMIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1980-06-10 | — | — | US | claimed |
| JP-8134037-A | — | — | None | — | — | JP | disclosed |
| CN-115151252-B | Iron death inhibitor-diarylamine acetamides | 维泰瑞隆有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-117222731-A | Lysine bacillus strain for promoting plant growth and use thereof | 国立大学法人东海国立大学机构 | 2023-12-12 | — | — | CN | disclosed |
| CN-115996908-A | Antagonists of GPR39 proteins | 俄勒冈健康科学大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-113677666-A | Substituted bicyclic compounds as farnesoid X receptor modulators | 百时美施贵宝公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-107897194-A | Use of 5-phenyl-or 5-benzyl-2-isoxazoline-3-carboxylic acid esters for improving plant yield | 拜耳知识产权有限责任公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-103929956-B | Use of acylsulfonamides for improving plant yield | 拜耳知识产权有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103228141-B | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |
| US-4413009-A | N-((Alkylamino)carbonyl)-N-(((alkylamino)carbonyl)oxy)acylamides with antineoplastic activity | THE DOW CHEMICAL COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0086492-A2 | N-((alkylamino)carbonyl)-N-(((alkylamino)-carbonyl)oxy)acylamides with antineoplastic activity | THE DOW CHEMICAL COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |
| EP-0005882-B1 | A METHOD OF COMBATING ACARINE PESTS BY MEANS OF OXYIMINO-SUBSTITUTED CYCLOPROPANE-CARBOXYLATE ESTERS, Z-ISOMERS OF CERTAIN SUCH ESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-06-08 | — | — | EP | disclosed |
| US-4292325-A | Oxyimino-substituted (1R,cis)cyclopropanecarboxylate pesticides | SHELL OIL COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4282249-A | INSECTICIDES, ACARICIDES | SHELL OIL COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4254277-A | PESTICIDES | SHELL OIL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4225338-A | Urea derivatives, process for making the same and herbicidal composition containing the same | SCHERING A G (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4211792-A | Oxyimino-substituted (1R,trans)-cyclopropanecarboxylate pesticides | SHELL OIL COMPANY (US) | 1980-07-08 | — | — | US | disclosed |
| US-4211789-A | MITICIDES | SHELL OIL COMPANY (US) | 1980-07-08 | — | — | US | disclosed |