Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 15/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.59 |
| ▸ | FAP | Q12884 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4159848 | 1.00 | DPP4 (0.59) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4171016 | 0.95 | DPP4 (0.63) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4171014 | 0.95 | DPP4 (0.63) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4108438 | 0.95 | DPP4 (0.63) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8248410 | 0.87 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4168303 | 0.87 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4167916 | 0.87 | DPP4 (0.66) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13803837 | 0.86 | DPP4 (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13804096 | 0.86 | DPP4 (0.51) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4160015 | 0.85 | DPP4 (0.61) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912706-A4 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIE (IN) | 2009-05-27 | — | — | EP | disclosed |
| EP-1912706-A2 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | Aurigene Discovery Technologies Limited (IN) | 2008-04-23 | — | — | EP | disclosed |
| WO-2006134613-A2 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2006-12-21 | — | — | WO | disclosed |