⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266192 | 1.00 | — | — | |
| SCHEMBL10340745 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL3815702 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL28881912 | 0.78 | TSHR (0.53) | — | |
| SCHEMBL21811900 | 0.77 | — | — | |
| SCHEMBL3815710 | 0.75 | — | — | |
| SCHEMBL11467661 | 0.75 | — | — | |
| SCHEMBL21064874 | 0.73 | TSHR (1.00) | — | |
| SCHEMBL17751390 | 0.73 | TSHR (0.65) | — | |
| SCHEMBL10239103 | 0.73 | TSHR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623922-A | Preparation method and application of 1, 1-ethylene glycol diacetate | 河北鼎泰制药有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-115806484-A | Geosmin modifier and synthesis method thereof | 苏州科铭生物技术有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115572306-A | Synthesis method of novel silane coupling agent trioxy-triethoxy-iminodiacetic acid diethyl ester organosilane | 江苏省计量科学研究院(江苏省能源计量数据中心) | 2023-01-06 | — | — | CN | claimed |
| CN-119330873-A | In itramod Process for the preparation of intermediates | 成都克莱蒙医药科技有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4460330-A1 | CONJUGATES, COMPOSITIONS AND METHODS OF USE | Virtuoso Binco, Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| US-20240150293-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | VERNALIS (R&D) LTD (GB) | 2024-05-09 | — | — | US | disclosed |
| CN-117623922-A | Preparation method and application of 1, 1-ethylene glycol diacetate | 河北鼎泰制药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-114746394-B | Aryl propionic acid derivative, pharmaceutical composition, and preparation method and application thereof | 南京海融医药科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-4277892-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2023-11-22 | — | — | EP | disclosed |
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| US-20230241034-A1 | MICROTUBULE POLYMERIZATION INHIBITOR PRODRUGS AND METHODS OF USING THE SAME | UNIV MARYLAND (US) | 2023-08-03 | — | — | US | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4687867-A | Metallotetradecadiene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| EP-0195342-A2 | Preparation of gossyplureand 1-Metallo-5,9-tetradecadiene | PHILLIPS PETROLEUM COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4613614-A | Prostaglandin I2 ester and fat emulsion containing the same | THE GREEN CROSS CORPORATION (JP) | 1986-09-23 | — | — | US | disclosed |
| US-4609498-A | FROM 1,5-CYCLOOCTADIENE AND 1-HEXENE | PHILLIPS PETROLEUM COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4357331-A | 7αMethoxycephalosporin derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-11-02 | — | — | US | disclosed |
| US-4325951-A | 1-Oxadethiacephalosporin derivatives and antibacterial use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-04-20 | — | — | US | disclosed |
| US-4321231-A | IN TH PRESENCE OF AN ACID, USING A TELLURIUM OR SELENIUM COMPOUND | ATLANTIC RICHFIELD COMPANY (US) | 1982-03-23 | — | — | US | disclosed |