Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106476 | 0.99 | IGF1R (0.71) | IGF1RNAMPT | |
| SCHEMBL4100206 | 0.96 | IGF1R (0.70) | IGF1R | |
| SCHEMBL4107315 | 0.96 | IGF1R (0.72) | IGF1R | |
| SCHEMBL4099460 | 0.95 | IGF1R (0.69) | IGF1R | |
| SCHEMBL4111784 | 0.94 | IGF1R (0.69) | IGF1R | |
| SCHEMBL2934498 | 0.90 | IGF1R (0.74) | IGF1R | |
| SCHEMBL2938867 | 0.89 | IGF1R (0.73) | IGF1R | |
| SCHEMBL4112373 | 0.88 | IGF1R (0.77) | IGF1R | |
| SCHEMBL2995891 | 0.88 | IGF1R (0.77) | IGF1R | |
| SCHEMBL1880413 | 0.88 | IGF1R (0.54) | IGF1RNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082329-A1 | Novel Sulphur-Containing Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors | AVENTIS PHARMA S.A. (FR) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082329-A1 | Novel Sulphur-Containing Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors | CHUK, BRAF, CNKSR1 | IGF1R 1229/4885NAMPT 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.