Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072842 | 0.90 | TSHR (0.40) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18776183 | 0.87 | TSHR (0.51) | TSHREPHX1 | |
| SCHEMBL25993934 | 0.85 | TSHR (0.63) | TSHRTHRBALDH1A1MAPTMEN1 | |
| SCHEMBL11900914 | 0.85 | TSHR (0.63) | TSHRTHRBALDH1A1MAPTMEN1 | |
| SCHEMBL18495390 | 0.85 | TSHR (0.53) | TSHRTHRBALDH1A1MAPTMEN1 | |
| SCHEMBL20365713 | 0.85 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL18323042 | 0.84 | TSHR (0.58) | TSHRTHRBALDH1A1MAPTEPHX1 | |
| SCHEMBL13103468 | 0.83 | TSHR (0.43) | TSHRTHRBALDH1A1MAPT | |
| SCHEMBL26743324 | 0.83 | TSHR (0.57) | TSHRTHRBALDH1A1MAPTEPHX1 | |
| SCHEMBL12462194 | 0.83 | TSHR (0.51) | TSHRALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9086528-B2 | Material for contact lenses, method for manufacturing contact lenses and contact lenses obtained thereby | BENQ MATERIALS CORPORATION (TW) | 2015-07-21 | — | — | US | disclosed |
| US-20150111983-A1 | MATERIAL FOR CONTACT LENSES, METHOD FOR MANUFACTURING CONTACT LENSES AND CONTACT LENSES OBTAINED THEREBY | BENQ MATERIALS CORPORATION (TW) | 2015-04-23 | — | — | US | disclosed |
| US-8952080-B2 | Material for contact lenses, method for manufacturing contact lenses and contact lenses obtained thereby | BENQ MATERIALS CORPORATION (TW) | 2015-02-10 | — | — | US | disclosed |
| US-20140221523-A1 | MATERIAL FOR CONTACT LENSES, METHOD FOR MANUFACTURING CONTACT LENSES AND CONTACT LENSES OBTAINED THEREBY | BENQ MATERIALS CORPORATION (TW) | 2014-08-07 | — | — | US | disclosed |
| US-8637589-B2 | Silicone prepolymer solutions | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8399539-B2 | Soluble silicone prepolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120065348-A1 | SOLUBLE SILICONE PREPOLYMERS | TORAY INDUSTRIES, INC. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20110077322-A1 | Silicone Prepolymer Solutions | TORAY INDUSTRIES, INC. (JP) | 2011-03-31 | — | — | US | disclosed |