SCHEMBL4110109

SCHEMBL4110109

O=C(O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OS(=O)(=O)CCC(F)(F)F)cc2)c1S(=O)(=O)CO

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 0.47
CNR2 P34972 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3080455 0.89 CNR1 (0.48) CNR1CNR2
SCHEMBL4611583 0.88 CNR2 (0.58) CNR1CNR2
SCHEMBL3080459 0.82 CNR1 (0.49) CNR1CNR2
SCHEMBL4893201 0.81 CNR2 (0.50) CNR1CNR2
SCHEMBL4110114 0.80 CNR1 (0.48) CNR1CNR2
SCHEMBL4661624 0.79 CNR2 (0.48) CNR1CNR2
SCHEMBL4612098 0.79 CNR2 (0.54) CNR1CNR2
SCHEMBL4903919 0.79 CNR1 (0.45) CNR1
SCHEMBL4908643 0.78 CNR1 (0.62) CNR1CNR2
SCHEMBL4612439 0.78 CNR1 (0.46) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2035389-A1 THERAPEUTIC AGENTS AstraZeneca AB (SE) 2009-03-18 EP disclosed
WO-2007148062-A1 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2007-12-27 WO disclosed