Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICOSLG | O75144 | 11/20 | 0.61 |
| ▸ | ICOS | Q9Y6W8 | 11/20 | 0.61 |
| ▸ | CHUK | O15111 | 15/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847741 | 0.94 | ICOSLG (0.60) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847512 | 0.92 | ICOSLG (0.58) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847504 | 0.92 | ICOSLG (0.61) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847586 | 0.90 | ICOSLG (0.60) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL4265538 | 0.90 | ICOSLG (0.60) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847716 | 0.89 | ICOSLG (0.59) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847516 | 0.89 | ICOSLG (0.55) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847503 | 0.87 | ICOSLG (0.59) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL3994817 | 0.86 | ICOSLG (0.63) | ICOSLGICOSCHUKMEN1IKBKB | |
| SCHEMBL13847527 | 0.86 | ICOSLG (0.63) | ICOSLGICOSCHUKMEN1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067233-A1 | BETA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009067233-A1 | BETA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | WO | disclosed |