⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL14908947 | 0.98 | — | — | |
| SCHEMBL31084796 | 0.84 | BTK (0.46) | — | |
| SCHEMBL31084799 | 0.84 | BTK (0.46) | — | |
| SCHEMBL31084800 | 0.84 | BTK (0.46) | — | |
| SCHEMBL4089866 | 0.84 | BTK (0.46) | — | |
| SCHEMBL15078163 | 0.84 | BTK (0.46) | — | |
| SCHEMBL31084797 | 0.84 | BTK (0.46) | — | |
| SCHEMBL31084801 | 0.84 | BTK (0.46) | — | |
| SCHEMBL31084798 | 0.84 | BTK (0.46) | — | |
| SCHEMBL1503908 | 0.83 | MME (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024120275-A1 | PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF | 浙江华海药业股份有限公司 | 2024-06-13 | — | — | WO | claimed |
| EP-2980090-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | Daiichi Sankyo Co., Ltd. (JP) | 2016-02-03 | — | — | EP | claimed |
| WO-2024120275-A1 | PREPARATION METHOD FOR EDOXABAN AND INTERMEDIATE THEREOF | 浙江华海药业股份有限公司 | 2024-06-13 | — | — | WO | disclosed |
| WO-2019004114-A1 | PRODUCTION METHOD FOR DIAMINE DERIVATIVE BY FLOW SYNTHESIS | 第一三共株式会社 | 2019-01-03 | — | — | WO | disclosed |
| EP-2602242-B1 | PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST | DAIICHI SANKYO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-2980067-B1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2589590-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO CO LTD (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| EP-1925611-B1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-2980067-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2980090-A1 | METHOD FOR PRODUCING (1S,4S,5S)-4-BROMO-6-OXABICYCLO[3.2.1]OCTAN-7-ONE | Daiichi Sankyo Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2407450-B1 | Method for producing optically active diamine derivative | DAIICHI SANKYO CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8901345-B2 | Process for preparation of optically active diamine derivative salt | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-27 | — | — | US | disclosed |
| EP-2602242-A1 | PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20130144061-A1 | PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-06 | — | — | US | disclosed |
| EP-2589590-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-8357808-B2 | Process for producing diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20090105491-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1925611-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-05-28 | — | — | EP | disclosed |