⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094106 | 1.00 | — | — | |
| SCHEMBL9878562 | 0.97 | — | — | |
| SCHEMBL60367 | 0.97 | — | — | |
| SCHEMBL10771605 | 0.93 | — | — | |
| SCHEMBL19664757 | 0.93 | — | — | |
| SCHEMBL14110155 | 0.93 | — | — | |
| SCHEMBL10446072 | 0.93 | — | — | |
| SCHEMBL23530995 | 0.93 | — | — | |
| SCHEMBL25238619 | 0.93 | — | — | |
| SCHEMBL20447983 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016013-A1 | METHOD OF MAKING 2,7-DIMETHYL-2,4,6-OCTATRIENEDIAL, A KEY INTERMEDIATE IN THE COMMERCIAL SYNTHESES OF VARIOUS CAROTENOIDS | LOYOLA UNIVERSITY OF CHICAGO (US) | 1996-05-30 | — | — | WO | claimed |
| US-5471005-A | Method of making 2,7-dimethyl-2,4,6-octatrienedial, a key intermediate in the commercial syntheses of various carotenoids | LOYOLA UNIVERSITY OF CHICAGO (US) | 1995-11-28 | — | — | US | claimed |
| US-5276200-A | Reacting acetone, methyl formate and sodium methoxide in methanol | UBE INDUSTRIES, LTD. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-4499630-A1 | BCL-XL INHIBITORS | BeiGene, Ltd. (KY) | 2025-02-05 | — | — | EP | disclosed |
| US-20250034128-A1 | BCL-XL INHIBITORS | BEIGENE, LTD. (KY) | 2025-01-30 | — | — | US | disclosed |
| WO-2023185986-A1 | BCL-XL INHIBITORS | BEIGENE , LTD. (KY) | 2023-10-05 | — | — | WO | disclosed |
| EP-3487903-A1 | HIGH TEMPERATURE-RESISTANT POLYISOCYANURATE FOAMS | Covestro Deutschland AG (DE) | 2019-05-29 | — | — | EP | disclosed |
| CN-105481702-B | The method of one pot process m-phenetidine | 浙江鸿盛化工有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-104193601-B | A kind of novel method preparing 3-methyl-2-amylene-4-alkynes-1-aldehyde | SICHUAN UNIVERSITY (CN) | 2016-03-02 | — | — | CN | disclosed |
| US-9150561-B2 | Thiazole derivatives and use thereof | MERCK SERONO S.A. (CH) | 2015-10-06 | — | — | US | disclosed |
| CN-104193601-A | A novel method for preparing 3-methyl-pent-2-en-4-yn-1-al | UNIV SICHUAN | 2014-12-10 | — | — | CN | disclosed |
| CN-1926121-A | Thiazole derivatives and uses thereof | APPLIED RESEARCH SYSTEMS (AN) | 2007-03-07 | — | — | CN | disclosed |
| EP-1709019-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2006-10-11 | — | — | EP | disclosed |
| WO-2006046071-A1 | COMPOUNDS AND COMPOSITIONS USEFUL IN THE TREATMENT OF NEOPLASIA | NIPRI LIMITED (GB) | 2006-05-04 | — | — | WO | disclosed |
| WO-2005068444-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-07-28 | — | — | WO | disclosed |
| CN-1136195-C | Process for synthesizing 3-alkyl-5-pyrazole carboxylate | 四川省化学工业研究设计院 | 2004-01-28 | — | — | CN | disclosed |
| CN-1305996-A | Process for synthesizing 3-alkyl-5-pyrazole carboxylate | SICHUAN PROV DESIGN INST OF CH (CN) | 2001-08-01 | — | — | CN | disclosed |
| US-5276200-A | Reacting acetone, methyl formate and sodium methoxide in methanol | UBE INDUSTRIES, LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| US-5276200-A | Reacting acetone, methyl formate and sodium methoxide in methanol | UBE INDUSTRIES, LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| US-5276200-A | Reacting acetone, methyl formate and sodium methoxide in methanol | UBE INDUSTRIES, LTD. (JP) | 1994-01-04 | — | — | US | disclosed |