SCHEMBL411692

SCHEMBL411692

CC(NCc1ccccc1)C(N)=O

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.57
MAOB P27338 2/20 0.56
MAOA P21397 1/20 0.56
SIGMAR1 Q99720 1/20 0.52
MAPT P10636 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ITGB1 P05556 1/20 0.50
ITGA5 P08648 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790979 1.00 SCN9A (0.57) SCN9AMAOBMAOASIGMAR1MAPT
Hydrochloric Acid SCHEMBL5966887 0.98 SCN9A (0.56) SCN9AMAOBMAOASIGMAR1MAPT
SCHEMBL7395238 0.93 SCN9A (0.55) SCN9AMAOBMAOAITGB1ITGA5
SCHEMBL7401755 0.93 SCN9A (0.55) SCN9AMAOBMAOAITGB1ITGA5
SCHEMBL7399338 0.93 SCN9A (0.55) SCN9AMAOBMAOAITGB1ITGA5
SCHEMBL7395231 0.93 SCN9A (0.55) SCN9AMAOBMAOAITGB1ITGA5
SCHEMBL3290662 0.93 SCN9A (0.55) SCN9AMAOBMAOAL3MBTL1ITGB1
SCHEMBL3289039 0.93 SCN9A (0.55) SCN9AMAOBMAOAL3MBTL1ITGB1
SCHEMBL7390817 0.89 FFAR1 (0.54) SCN9AMAOBMAOA
SCHEMBL7390821 0.89 FFAR1 (0.54) SCN9AMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535310-B1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS COCA COLA CO (US) 2025-12-24 EP claimed
US-11708454-B2 Acrolein scavenging in PTF and other 1,3-propanediol derived polymers THE COCA-COLA COMPANY (US) 2023-07-25 US claimed
US-20190330420-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS THE COCA-COLA COMPANY (US) 2019-10-31 US claimed
EP-3535310-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS The Coca-Cola Company (US) 2019-09-11 EP claimed
CN-109996830-A Acrolein scavenger in PTF and other 1, 3-propanediol derived polymers 可口可乐公司 2019-07-09 CN claimed
US-20080166359-A1 Methods of using MEK inhibitors EXELIXIS, INC. 2008-07-10 US claimed
WO-1995021814-A1 NOVEL DERIVATIVES OF TETRAMETHYLCYCLOPROPANE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1995-08-17 WO claimed
EP-3535310-B1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS COCA COLA CO (US) 2025-12-24 EP disclosed
US-11708454-B2 Acrolein scavenging in PTF and other 1,3-propanediol derived polymers THE COCA-COLA COMPANY (US) 2023-07-25 US disclosed
US-20190330420-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS THE COCA-COLA COMPANY (US) 2019-10-31 US disclosed
EP-3535310-A1 ACROLEIN SCAVENGING IN PTF AND OTHER 1,3-PROPANEDIOL DERIVED POLYMERS The Coca-Cola Company (US) 2019-09-11 EP disclosed
CN-109996830-A Acrolein scavenger in PTF and other 1, 3-propanediol derived polymers 可口可乐公司 2019-07-09 CN disclosed
CN-105722516-A A method for treating infection, sepsis and injury 低温药理KF有限公司 2016-06-29 CN disclosed
EP-1438956-A1 Alpha-aminoamide derivatives useful as antimigraine agents Newron Pharmaceuticals S.p.A. (IT) 2004-07-21 EP disclosed
EP-1045830-B1 ALPHA-AMINOAMIDE DERIVATIVES USEFUL AS ANALGESIC AGENTS NEWRON PHARM SPA (IT) 2003-04-23 EP disclosed
US-6306903-B1 ANALGESICS FOR ALLEVIATION OF CHRONIC AND NEUROPATHIC PAIN. NEWRON PHARMACEUTICALS S.P.A. (IT) 2001-10-23 US disclosed
EP-1045830-A1 ALPHA-AMINOAMIDE DERIVATIVES USEFUL AS ANALGESIC AGENTS Newron Pharmaceuticals S.p.A. (IT) 2000-10-25 EP disclosed
WO-1999035125-A1 ALPHA-AMINOAMIDE DERIVATIVES USEFUL AS ANALGESIC AGENTS NEWRON PHARMACEUTICALS S.P.A. (IT) 1999-07-15 WO disclosed
US-5672615-A MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS NOVARTIS CORPORATION (US) 1997-09-30 US disclosed
WO-1995021814-A1 NOVEL DERIVATIVES OF TETRAMETHYLCYCLOPROPANE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1995-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166359-A1 Methods of using MEK inhibitors BRAF, NRAS, KRAS SCN9A 3634/4885MAOB 2501/4885MAOA 3624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.