Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 7/20 | 0.70 |
| ▸ | CA7 | P43166 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | BRAF | P15056 | 3/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 2/20 | 0.62 |
| ▸ | RAF1 | P04049 | 6/20 | 0.62 |
| ▸ | RET | P07949 | 2/20 | 0.60 |
| ▸ | PLK4 | O00444 | 1/20 | 0.60 |
| ▸ | CIT | O14578 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12319881 | 0.86 | KDR (0.76) | LMNAMAPTSMN1; SMN2KDRCA7 | |
| SCHEMBL26077943 | 0.85 | KDR (0.67) | LMNAALDH1A1MAPTSMN1; SMN2KDR | |
| SCHEMBL4117940 | 0.84 | MAPT (0.66) | LMNAALDH1A1MAPTSMN1; SMN2CA9 | |
| SCHEMBL118026 | 0.84 | KDR (1.00) | KDRCA7CA9CA1CA2 | |
| SCHEMBL29364392 | 0.84 | KDR (1.00) | KDRCA7CA9CA1CA2 | |
| SCHEMBL13945707 | 0.84 | KDR (0.72) | KDRCA7CA9CA1CA2 | |
| SCHEMBL3790500 | 0.83 | KDR (0.64) | KDRCA7CA9CA1CA2 | |
| SCHEMBL12310641 | 0.83 | KDR (0.76) | LMNAALDH1A1MAPTKDRCA7 | |
| SCHEMBL28901340 | 0.83 | KDR (0.76) | KDRCA7CA9CA1CA2 | |
| SCHEMBL16628055 | 0.83 | RAF1 (0.63) | KDRCA7CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | LMNA 4283/4885ALDH1A1 994/4885MAPT 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.