Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 14/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269091 | 1.00 | MAPT (0.39) | MAPTDPP4DPP7ATMDPP9 | |
| Hydrochloric Acid SCHEMBL270688 | 0.99 | MAPT (0.39) | MAPTDPP4DPP7ATMDPP9 | |
| SCHEMBL269148 | 0.82 | SCN9A (0.45) | MAPTATMP2RY1 | |
| SCHEMBL269147 | 0.82 | SCN9A (0.45) | MAPTATMP2RY1 | |
| SCHEMBL270520 | 0.79 | ALOX5AP (0.40) | DPP4DPP7DPP9DPP8CARM1 | |
| Hydrochloric Acid SCHEMBL269767 | 0.79 | ALOX5AP (0.39) | DPP4DPP7DPP9DPP8CARM1 | |
| Hydrochloric Acid SCHEMBL3989995 | 0.79 | ALOX5AP (0.39) | DPP4DPP7DPP9DPP8CARM1 | |
| SCHEMBL269523 | 0.73 | DPP4 (0.47) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL267788 | 0.71 | ALOX5AP (0.38) | MAPTCARM1PRMT6SMN1; SMN2 | |
| SCHEMBL269072 | 0.71 | ALOX5AP (0.40) | CARM1PRMT6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912946-B1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | LILLY CO ELI (US) | 2009-05-27 | — | — | EP | disclosed |