Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119272 | 1.00 | CHRM5 (0.52) | CHRM5ADRA2CCCR1SMN1; SMN2MAPT | |
| SCHEMBL15191011 | 0.98 | CHRM5 (0.48) | CHRM5ADRA2CCCR1SMN1; SMN2MAPT | |
| SCHEMBL15130431 | 0.98 | CHRM5 (0.48) | CHRM5ADRA2CCCR1SMN1; SMN2MAPT | |
| SCHEMBL4909423 | 0.87 | CCR1 (0.50) | CCR1SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL5555057 | 0.86 | CCR1 (0.60) | CHRM5ADRA2CCCR1SMN1; SMN2CHRM2 | |
| SCHEMBL27232352 | 0.83 | CHRM3 (0.49) | CHRM5CCR1CHRM2CHRM1CHRM3 | |
| SCHEMBL27224933 | 0.83 | CHRM3 (0.49) | CHRM5CCR1CHRM2CHRM1CHRM3 | |
| SCHEMBL6118868 | 0.83 | PDE7A (0.47) | CCR1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6118864 | 0.83 | PDE7A (0.47) | CCR1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL27204675 | 0.81 | KDM2B (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071519-A9 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009071519-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |