Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 14/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119967 | 1.00 | FDFT1 (0.49) | FDFT1ATMALDH1A1TSHR | |
| SCHEMBL4119962 | 1.00 | FDFT1 (0.49) | FDFT1ATMALDH1A1TSHR | |
| SCHEMBL4122998 | 0.92 | FDFT1 (0.58) | FDFT1 | |
| SCHEMBL4122996 | 0.92 | FDFT1 (0.58) | FDFT1 | |
| SCHEMBL4122992 | 0.92 | FDFT1 (0.58) | FDFT1 | |
| SCHEMBL4124478 | 0.92 | FDFT1 (0.50) | FDFT1ATMALDH1A1TSHR | |
| SCHEMBL13775945 | 0.92 | FDFT1 (0.41) | FDFT1ALDH1A1 | |
| SCHEMBL4128981 | 0.92 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL4128988 | 0.92 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL4128986 | 0.92 | FDFT1 (0.52) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | FDFT1, COASY, HMGCR | FDFT1 1/4885ATM 2628/4885ALDH1A1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.