SCHEMBL4121836

SCHEMBL4121836

CCCOc1cc2c(OCCC)cccc2cc1CC=C1SC(Nc2ccc(CC(=O)O)c(C(C)O)c2)=NC1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635223 0.91 MEN1 (0.39) MEN1KMT2A
SCHEMBL4635225 0.79 KMT2A (0.40) MEN1KMT2A
SCHEMBL4128848 0.76 MEN1 (0.43) MEN1KMT2A
SCHEMBL4128846 0.76 MEN1 (0.43) MEN1KMT2A
SCHEMBL4131927 0.72 KMT2A (0.42) MEN1KMT2A
SCHEMBL4131931 0.72 KMT2A (0.42) MEN1KMT2A
SCHEMBL4127484 0.71 MEN1 (0.39) MEN1KMT2A
SCHEMBL4127491 0.71 MEN1 (0.39) MEN1KMT2A
SCHEMBL4127235 0.71 KMT2A (0.39) MEN1KMT2A
SCHEMBL4127754 0.68 KMT2A (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088432-A1 Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors TORRENT PHARMACEUTICALS LIMITED (IN) 2009-04-02 US claimed
US-20090088432-A1 Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors TORRENT PHARMACEUTICALS LIMITED (IN) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088432-A1 Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors PTPRF, PTPA, PTPRJ MEN1 4075/4885KMT2A 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.