Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.48 |
| ▸ | GLRB | P48167 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114838 | 0.88 | GLRA3 (0.46) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL5062113 | 0.87 | GLRA3 (0.50) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4134003 | 0.82 | GLRA3 (0.50) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4129099 | 0.82 | GLRA3 (0.53) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4127647 | 0.81 | GLRA3 (0.47) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4129271 | 0.81 | GLRA3 (0.47) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4113656 | 0.81 | GLRA3 (0.47) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4121706 | 0.81 | GLRA3 (0.49) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4122301 | 0.80 | GLRA3 (0.44) | GLRA3GLRBTP53SMN1; SMN2HIF1A | |
| SCHEMBL4121770 | 0.80 | GLRA3 (0.50) | GLRA3GLRBTP53SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192190-A1 | Benzoic Acid Derivatives that are Modulators or Agonists of GlyR | GLRA1, GLRB, GPBAR1 | GLRA3 6/4885GLRB 2/4885TP53 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.