Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 7/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112201 | 0.83 | KDM4E (0.54) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL4118526 | 0.83 | MAPT (0.66) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL4121665 | 0.82 | KMT2A (0.58) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL30568974 | 0.82 | KCNQ3 (0.64) | SMN1; SMN2NPSR1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL6361424 | 0.82 | KCNQ3 (0.64) | SMN1; SMN2NPSR1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL4115660 | 0.81 | KMT2A (0.58) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL4112815 | 0.81 | SMARCA2 (0.64) | KMT2ALMNAMEN1MAPTHTT | |
| SCHEMBL4119219 | 0.81 | KDM4E (0.77) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL22092668 | 0.81 | KCNQ3 (0.71) | KMT2ALMNAMEN1SMN1; SMN2RAB9A | |
| SCHEMBL4115554 | 0.81 | MEN1 (0.59) | KMT2ALMNAMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | claimed |
| EP-1804785-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006049941-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-05-11 | — | — | WO | claimed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | KMT2A 2807/4885LMNA 4283/4885MEN1 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.