SCHEMBL4125067

SCHEMBL4125067

CC(OC(CO)CO)C(O)CO

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.33
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8737588 0.86 CYP2C9 (0.32) TDP1LMNAL3MBTL1TSHR
SCHEMBL2305046 0.86 TDP1 (0.44) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL14781398 0.81 TDP1 (0.40) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL15800142 0.81 TDP1 (0.40) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL25870351 0.81 TDP1 (0.40) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL23819364 0.81 TDP1 (0.40) TDP1TSHR
SCHEMBL16729297 0.79 TDP1 (0.38) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL14599632 0.79 TDP1 (0.38) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL15731250 0.79 TDP1 (0.38) TDP1LMNAL3MBTL1TSHRKDM4E
SCHEMBL16729401 0.79 TDP1 (0.38) TDP1LMNAL3MBTL1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012097052-A2 MONOSACCHARIDE-BASED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE AND INFLAMMATORY DERMATOLOGICAL DISEASES INTERTECH BIO, LLC (US) 2012-07-19 WO disclosed
US-20120114595-A1 SUGAR CHAIN-ADDED AILIM EXTRACELLULAR DOMAIN AND METHOD FOR PRODUCING SAME OTSUKA CHEMICAL CO., LTD. (JP) 2012-05-10 US disclosed
EP-2052252-B1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE ABACUS DIAGNOSTICA OY (FI) 2010-11-10 EP disclosed
EP-1938836-A1 Compositions comprising a B subunit of shiga toxin and a means stimulating NKT cells UNIVERSITE RENE DESCARTES (PARIS V) (FR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114595-A1 SUGAR CHAIN-ADDED AILIM EXTRACELLULAR DOMAIN AND METHOD FOR PRODUCING SAME SIGLEC7, ENGASE, SIGLEC9 TDP1 3396/4885LMNA 2462/4885L3MBTL1 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.