Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.49 |
| ▸ | CNR2 | P34972 | 7/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933664 | 0.91 | CNR1 (0.46) | CNR1CNR2PTPN1MAPTDRD2 | |
| SCHEMBL3216067 | 0.91 | CNR1 (0.42) | CNR1CNR2PTPN1DRD2DRD3 | |
| SCHEMBL3201537 | 0.90 | CNR1 (0.43) | CNR1CNR2PTPN1MAPT | |
| SCHEMBL2929598 | 0.90 | PTPN1 (0.44) | CNR1CNR2PTPN1MAPTDRD2 | |
| SCHEMBL3220485 | 0.89 | PTPN1 (0.43) | CNR1CNR2PTPN1 | |
| SCHEMBL3217932 | 0.89 | CNR1 (0.41) | CNR1CNR2PTPN1 | |
| SCHEMBL3217863 | 0.89 | PTPN1 (0.46) | CNR1CNR2PTPN1MAPTDRD2 | |
| SCHEMBL2930659 | 0.89 | CNR1 (0.42) | CNR1CNR2PTPN1MAPTDRD2 | |
| SCHEMBL2930641 | 0.88 | PTPN1 (0.44) | CNR1CNR2PTPN1MAPTDRD2 | |
| SCHEMBL3929110 | 0.88 | CNR1 (0.41) | CNR1CNR2PTPN1MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038267-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | Novartis AG (CH) | 2009-03-25 | — | — | EP | claimed |
| WO-2007115058-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | claimed |