SCHEMBL4129981

SCHEMBL4129981

CCCCCCCCOc1ccc(-c2ccc(O)cc2)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.70
LTA4H P09960 3/20 0.61
ALDH2 P05091 1/20 0.60
PTPN11 Q06124 4/20 0.58
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
ALDH1A1 P00352 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CNR2 P34972 5/20 0.53
RARB P10826 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504179 0.92 NR5A1 (0.62) NR5A1LTA4HALDH2PTPN11MEN1
SCHEMBL22264596 0.92 NR5A1 (0.62) NR5A1LTA4HALDH2PTPN11MEN1
SCHEMBL7941538 0.89 PTPN11 (0.59) NR5A1LTA4HALDH2PTPN11MEN1
SCHEMBL17388694 0.89 PTPN11 (0.59) NR5A1LTA4HALDH2PTPN11MEN1
SCHEMBL26331612 0.88 NR5A1 (0.62) NR5A1LTA4HALDH2PTPN11MEN1
SCHEMBL6417256 0.87 NR5A1 (0.55) NR5A1LTA4HALDH2PTPN11MEN1
Formaldehyde SCHEMBL27947148 0.85 PTPN11 (0.59) NR5A1ALDH2PTPN11MEN1NPC1
SCHEMBL10536480 0.85 NR5A1 (0.89) NR5A1LTA4HALDH2NPC1GAA
SCHEMBL9225728 0.85 NR5A1 (0.89) NR5A1LTA4HALDH2NPC1GAA
SCHEMBL5688520 0.85 NR5A1 (0.89) NR5A1LTA4HALDH2NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4966883-A LAYER COMPRISING A LEUCO DYE, A PHENOLIC DEVELOPER, AND A PSEUDO DEVELOPER JAMES RIVER GRAPHICS, INC. (US) 1990-10-30 US claimed
WO-1990002158-A1 A COMPOSITION FOR USE IN THERMALLY SENSITIVE COATINGS AND A THERMALLY SENSITIVE RECORDING MATERIAL JAMES RIVER GRAPHICS INC. (US) 1990-03-08 WO claimed
EP-2066702-A1 POLYMER ADDITIVES CONTAINING PARTICLES BASF SE (DE) 2009-06-10 EP disclosed
WO-2008034813-A1 POLYMER ADDITIVES CONTAINING PARTICLES BASF SE (DE) 2008-03-27 WO disclosed
US-4966883-A LAYER COMPRISING A LEUCO DYE, A PHENOLIC DEVELOPER, AND A PSEUDO DEVELOPER JAMES RIVER GRAPHICS, INC. (US) 1990-10-30 US disclosed
WO-1990002158-A1 A COMPOSITION FOR USE IN THERMALLY SENSITIVE COATINGS AND A THERMALLY SENSITIVE RECORDING MATERIAL JAMES RIVER GRAPHICS INC. (US) 1990-03-08 WO disclosed
US-4525516-A BUBBLE FREE MOLDFING PHILLIPS PETROLEUM COMPANY (US) 1985-06-25 US disclosed
EP-0028318-A1 Ethers based on polyalkyl-1-oxa-diazaspirodecanes, their preparation, their use and synthetic polymers stabilized therewith HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-13 EP disclosed
EP-0025867-A1 Alkylated diazaspirodecanes, their preparation and their use as light stabilisers HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-01 EP disclosed