SCHEMBL4130557

SCHEMBL4130557

CCCCN(C)c1ccc(N(C)CCCC)cc1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.66
TRPV1 Q8NER1 7/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18713238 0.93 MAPT (0.59) MAPTTRPV1KDM4EALDH1A1TDP1
SCHEMBL8484830 0.91 MAPT (0.58) MAPTTRPV1ALDH1A1
SCHEMBL6611848 0.89 MAPT (0.56) MAPTTRPV1KDM4EALDH1A1TDP1
SCHEMBL17195664 0.89 MAPT (0.56) MAPTTRPV1KDM4EALDH1A1TDP1
SCHEMBL6880118 0.89 MAPT (0.56) MAPTTRPV1KDM4EALDH1A1EGFR
SCHEMBL96161 0.88 MAPT (0.55) MAPTTRPV1TDP1
SCHEMBL14619177 0.87 MAPT (0.54) MAPT
SCHEMBL16846626 0.87 MAPT (0.54) MAPTKDM4EALDH1A1EGFRADRA2A
SCHEMBL12714225 0.87 MAPT (0.54) MAPTTRPV1KDM4EALDH1A1EGFR
SCHEMBL13261241 0.86 MAPT (0.53) MAPTTRPV1KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8303851-B2 Stabilizers, organic or inorganic pigments, and/orone or more dyes, obtained by extrusion at lowest melting temperature GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2012-11-06 US disclosed
US-7560048-B2 Liquid stabilizing mixtures for organic polymers GREAT LAKES CHEMICAL (EUROPE) GMBH (DE) 2009-07-14 US disclosed
US-20080194766-A1 Mixtures of Additives For Organic Polymers In Granular Form GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2008-08-14 US disclosed
US-20060089437-A1 Liquid stabilizing mixtures for organic polymers GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2006-04-27 US disclosed
EP-1097965-B1 Mixtures of additives for organic polymers in granular form GREAT LAKES CHEMICAL EUROP (CH) 2005-03-30 EP disclosed
US-20030189192-A1 Stabilizing mixtures for organic polymers GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2003-10-09 US disclosed
US-6605658-B1 Oxygen, heat and/or light resistance GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2003-08-12 US disclosed
US-20030144395-A1 Liquid stabilizing mixtures for organic polymers GREAT LAKES CHEMICAL (EUROPE) GMBH (DE) 2003-07-31 US disclosed
EP-1097965-A1 Mixtures of additives for organic polymers in granular form Great Lakes Chemical (Europe) GmbH (CH) 2001-05-09 EP disclosed
US-6090512-A PHOTORECEPTOR INCLUDING CONDUCTIVE SUBSTRATE AND PHOTOSENSITIVE LAYER CONTAINING ARYLAMINE COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2000-07-18 US disclosed
US-5079119-A Photoreceptor KONICA CORPORATION (JP) 1992-01-07 US disclosed