Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 6/20 | 0.36 |
| ▸ | GRK2 | P25098 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.36 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133496 | 1.00 | MAPT (0.43) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4129351 | 0.92 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4129359 | 0.92 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4123871 | 0.79 | POLB (0.51) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4123875 | 0.79 | POLB (0.51) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4133862 | 0.77 | DUSP22 (0.49) | ALDH1A1POLBDUSP3DUSP22GFER | |
| SCHEMBL4133860 | 0.77 | DUSP22 (0.49) | ALDH1A1POLBDUSP3DUSP22GFER | |
| SCHEMBL4138121 | 0.76 | NSD2 (0.43) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4138118 | 0.76 | NSD2 (0.43) | MAPTALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL4132445 | 0.74 | FFAR1 (0.47) | HTTDUSP3DUSP22LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | claimed |
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | PTPRF, PTPA, PTPRJ | MAPT 3532/4885ALDH1A1 216/4885KMT2A 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.