⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109403 | 0.67 | — | — | |
| SCHEMBL11109408 | 0.67 | — | — | |
| Formic Acid Methyl Ester SCHEMBL1330535 | 0.67 | — | — | |
| Formic Acid Methyl Ester SCHEMBL650 | 0.67 | — | — | |
| Formic Acid Methyl Ester SCHEMBL1332784 | 0.67 | — | — | |
| Formic Acid Methyl Ester SCHEMBL935999 | 0.67 | — | — | |
| Formic Acid Methyl Ester SCHEMBL10773235 | 0.63 | — | — | |
| Formic Acid Methyl Ester SCHEMBL14787285 | 0.63 | TDP1 (0.35) | — | |
| Formic Acid Methyl Ester SCHEMBL8027094 | 0.63 | — | — | |
| Formic Acid Methyl Ester SCHEMBL535983 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073353-B | Lignan derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-05-14 | — | — | CN | claimed |
| CN-114956977-B | Biphenyl compound, pharmaceutical composition, and preparation methods and applications thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114644560-B | Phenyl acrylic compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117304033-A | Caffeic acid derivative and preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2023-12-29 | — | — | CN | claimed |
| WO-2023236924-A1 | BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-12-14 | — | — | WO | claimed |
| WO-2023202559-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-10-26 | — | — | WO | claimed |
| CN-115073353-A | Lignan derivative and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | claimed |
| CN-111777501-B | Caffeic acid phenethyl ester derivatives, preparation method thereof, pharmaceutical compositions thereof and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | claimed |
| CN-114956977-A | Biphenyl compound, pharmaceutical composition, preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114644560-A | Phenyl acrylic compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| WO-2007031803-A2 | MOLECULAR RESISTS BASED ON FUNCTIONALIZED POLYCARBOCYCLES | NATIONAL CENTER FOR SCIENTIFIC RESEARCH (NCSR) ''DEMOKRITOS'' (GR) | 2007-03-22 | — | — | WO | claimed |
| US-6559241-B2 | Process for producing a hydrogenated polymer | KURARAY CO., LTD. (JP) | 2003-05-06 | — | — | US | claimed |
| US-20020137854-A1 | Process for producing a hydrogenated polymer | KURARAY CO. LTD. (JP) | 2002-09-26 | — | — | US | claimed |
| US-20020086895-A1 | Methods of treating fungal infections | CHU WAI-LAM ALEX (US) | 2002-07-04 | — | — | US | claimed |
| EP-1005338-A4 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1005338-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1999004789-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 1999-02-04 | — | — | WO | claimed |
| US-5384075-A | Curable polysiloxanes for adhesives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-01-24 | — | — | US | claimed |
| EP-0338887-B1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMA (US) | 1993-12-08 | — | — | EP | claimed |
| EP-0338887-A1 | Phosphonoalkylpurine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-10-25 | — | — | EP | claimed |